The Emerging Role of Outdoor and Indoor Air Pollution in Cardiovascular Disease
Identifieur interne : 000455 ( Main/Exploration ); précédent : 000454; suivant : 000456The Emerging Role of Outdoor and Indoor Air Pollution in Cardiovascular Disease
Auteurs : Jacinta C. Uzoigwe [États-Unis] ; Thavaleak Prum [États-Unis] ; Eric Bresnahan [États-Unis] ; Mahdi Garelnabi [États-Unis]Source :
- North American Journal of Medical Sciences [ 2250-1541 ] ; 2013.
Abstract
Outdoor and indoor air pollution poses a significant cardiovascular risk, and has been associated with atherosclerosis, the main underlying pathology in many cardiovascular diseases. Although, it is well known that exposure to air pollution causes pulmonary disease, recent studies have shown that cardiovascular health consequences of air pollution generally equal or exceed those due to pulmonary diseases. The objective of this article is to evaluate the current evidence on the emerging role of environmental air pollutions in cardiovascular disease, with specific focus on the types of air pollutants and mechanisms of air pollution-induced cardiotoxicity. Published literature on pollution was systematically reviewed and cited in this article. It is hoped that this review will provide a better understanding of the harmful cardiovascular effects induced by air pollution exposure. This will help to bring a better understanding on the possible preventive health measures and will also serve regulatory agencies and researchers. In addition, elucidating the biological mechanisms underlying the link between air pollution and cardiovascular disease is an essential target in developing novel pharmacological strategies aimed at decreasing adverse effects of air pollution on cardiovascular system.
Url:
DOI: 10.4103/1947-2714.117290
PubMed: 24083218
PubMed Central: 3784920
Affiliations:
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Uzoigwe</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Clinical Laboratory and Nutritional Sciences, University of Massachusetts Lowell, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical Laboratory and Nutritional Sciences, University of Massachusetts Lowell, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Prum, Thavaleak" sort="Prum, Thavaleak" uniqKey="Prum T" first="Thavaleak" last="Prum">Thavaleak Prum</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Clinical Laboratory and Nutritional Sciences, University of Massachusetts Lowell, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical Laboratory and Nutritional Sciences, University of Massachusetts Lowell, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Bresnahan, Eric" sort="Bresnahan, Eric" uniqKey="Bresnahan E" first="Eric" last="Bresnahan">Eric Bresnahan</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Clinical Laboratory and Nutritional Sciences, University of Massachusetts Lowell, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical Laboratory and Nutritional Sciences, University of Massachusetts Lowell, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Garelnabi, Mahdi" sort="Garelnabi, Mahdi" uniqKey="Garelnabi M" first="Mahdi" last="Garelnabi">Mahdi Garelnabi</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Clinical Laboratory and Nutritional Sciences, University of Massachusetts Lowell, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical Laboratory and Nutritional Sciences, University of Massachusetts Lowell, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author></analytic><series><title level="j">North American Journal of Medical Sciences</title><idno type="ISSN">2250-1541</idno><idno type="eISSN">1947-2714</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Outdoor and indoor air pollution poses a significant cardiovascular risk, and has been associated with atherosclerosis, the main underlying pathology in many cardiovascular diseases. Although, it is well known that exposure to air pollution causes pulmonary disease, recent studies have shown that cardiovascular health consequences of air pollution generally equal or exceed those due to pulmonary diseases. The objective of this article is to evaluate the current evidence on the emerging role of environmental air pollutions in cardiovascular disease, with specific focus on the types of air pollutants and mechanisms of air pollution-induced cardiotoxicity. Published literature on pollution was systematically reviewed and cited in this article. It is hoped that this review will provide a better understanding of the harmful cardiovascular effects induced by air pollution exposure. This will help to bring a better understanding on the possible preventive health measures and will also serve regulatory agencies and researchers. In addition, elucidating the biological mechanisms underlying the link between air pollution and cardiovascular disease is an essential target in developing novel pharmacological strategies aimed at decreasing adverse effects of air pollution on cardiovascular system.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Pope, Ca" uniqKey="Pope C">CA Pope</name></author><author><name sortKey="Burnett, Rt" uniqKey="Burnett R">RT Burnett</name></author><author><name sortKey="Thun, Mj" uniqKey="Thun M">MJ Thun</name></author><author><name sortKey="Calle, Ee" uniqKey="Calle E">EE Calle</name></author><author><name sortKey="Krewski, D" uniqKey="Krewski D">D Krewski</name></author><author><name sortKey="Ito, K" uniqKey="Ito K">K Ito</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pope, Ca" uniqKey="Pope C">CA Pope</name></author><author><name sortKey="Burnett, Rt" uniqKey="Burnett 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Cesana</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oliver, Lc" uniqKey="Oliver L">LC Oliver</name></author><author><name sortKey="Weber, Rp" uniqKey="Weber R">RP Weber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vanhoorne, M" uniqKey="Vanhoorne M">M Vanhoorne</name></author><author><name sortKey="De Bacquer, D" uniqKey="De Bacquer D">D De Bacquer</name></author><author><name sortKey="De Backer, G" uniqKey="De Backer G">G De Backer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drexler, H" uniqKey="Drexler H">H Drexler</name></author><author><name sortKey="Ulm, K" uniqKey="Ulm K">K Ulm</name></author><author><name sortKey="Hubmann, M" uniqKey="Hubmann M">M Hubmann</name></author><author><name sortKey="Hardt, R" uniqKey="Hardt R">R Hardt</name></author><author><name sortKey="Goen, T" uniqKey="Goen T">T Goen</name></author><author><name sortKey="Mondorf, W" uniqKey="Mondorf W">W Mondorf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Omae, K" uniqKey="Omae K">K Omae</name></author><author><name sortKey="Takebayashi, T" uniqKey="Takebayashi T">T Takebayashi</name></author><author><name sortKey="Nomiyama, T" uniqKey="Nomiyama T">T Nomiyama</name></author><author><name sortKey="Ishizuka, C" uniqKey="Ishizuka C">C Ishizuka</name></author><author><name sortKey="Nakashima, H" uniqKey="Nakashima H">H Nakashima</name></author><author><name sortKey="Uemura, T" uniqKey="Uemura T">T Uemura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kotseva, Kp" uniqKey="Kotseva K">KP Kotseva</name></author><author><name sortKey="De Bacquer, D" uniqKey="De Bacquer D">D De Bacquer</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Massachusetts</li></region></list><tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Uzoigwe, Jacinta C" sort="Uzoigwe, Jacinta C" uniqKey="Uzoigwe J" first="Jacinta C." last="Uzoigwe">Jacinta C. Uzoigwe</name></region><name sortKey="Bresnahan, Eric" sort="Bresnahan, Eric" uniqKey="Bresnahan E" first="Eric" last="Bresnahan">Eric Bresnahan</name><name sortKey="Garelnabi, Mahdi" sort="Garelnabi, Mahdi" uniqKey="Garelnabi M" first="Mahdi" last="Garelnabi">Mahdi Garelnabi</name><name sortKey="Prum, Thavaleak" sort="Prum, Thavaleak" uniqKey="Prum T" first="Thavaleak" last="Prum">Thavaleak Prum</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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